Dear Dr. Jody: Our eight year old bulldog, “Porkchop”, has gradually
developed a cloudy appearance in both eyes.
She doesn’t seem painful at all, but she has started bumping into walls
in dim light. Are these cataracts, and
if so, what can we do about them?
The inner anatomy of the eye is
very complicated. A simplified
explanation is that the outer, clear layer of the eye (the part that your
contact lenses adhere to) is called the cornea.
The coloured part of the eye is called the iris, and the little black “hole”
in the middle of the iris is called the lens.
In front of the lens is a chamber of fluid called the aqueous humor, and
behind the lens is another chamber of fluid, called the vitreous humor.
The lens is not really just a
little black hole in the iris. It is
actually a little fibre-filled sac that can quickly change shape in response to
different conditions. It is this dynamic
little Smartie-shaped structure that allows you to focus on objects at
different distances.
As dogs age, more and more fibres
are deposited inside the lens. Because
the lens cannot grow and become larger to accommodate these fibres, the fibres
become more compacted together and give the lens a cloudy appearance. This cloudy lens is not necessarily a
cataract, and is usually a condition called lenticular sclerosis (which
essentially means “fibrous lens”). Most
dogs can still see quite well through these cloudy lenses, and they are not
painful.
Cataracts on the other hand,
while they can develop as a result of age, more often develop for other reasons
including genetics, trauma, or disease such as diabetes. In diabetic patients, not only is blood sugar
elevated beyond the normal range, but eye glucose is also elevated. Excess glucose in the aqueous chamber of the
eye is absorbed by the lens where it is converted into sorbitol. The sorbitol within the lens then osmotically
draws water into the lens. This concoction
results in the formation of a completely opaque cataract, which the dog cannot
see through. It is not unusual for
diabetic cataracts to develop quickly – at times within several hours.
While not all cataracts are
painful, many are. Often, the body’s
immune system recognizes the abnormal consistency of the lens as foreign, and
mounts an immune response against it.
This causes a great deal of inflammation within the eye, and
consequently the eye becomes very uncomfortable. Additionally, the abnormal lens can loosen
from the tissue strands that hold it in place within the iris. This process, known as a lens luxation, causes
the cataractous lens to float free within the front chamber of the eye. This acutely painful condition requires
immediate medical attention. If the lens
slips into the front chamber of the eye, it can obstruct the normal drainage of
fluid from the eye and cause a sudden increase in pressure within the globe – a
highly painful condition known as glaucoma.
Eyes are wonderfully complex
structures that are beautifully designed.
However, sometimes even the smallest of changes can lead to permanent
vision loss or intense pain. If you
believe that the appearance of your dog’s eyes has changed in any way, it is
important to consult your veterinarian immediately. While some lens opacities are a normal,
non-painful result of the ageing process, many are not. In some cases, even though the dog does not
act painful, there can be significant inflammation within the eye that, if not
diagnosed and treated quickly, can progress to permanent loss of vision or even
the need to remove the eye surgically.
Ethosheaven have some wonderful drops for cataracts called bright eyes, thousands of people and pets have used them with great results.
ReplyDeleteLeo-125, thank you for your comment.
ReplyDeleteThe active ingredient in BrightEyes is N-Acetyl-Carnosine. A literature search on the research and development behind BrightEyes reveals a published article in Veterinary Ophthalmology (2006 Sep-Oct;9(5):311-6) entitled "The effect of a topical antioxidant formulation including N-acetyl carnosine on canine cataract: a preliminary study" concluded that there was no statistically significant improvement in 58 cataracts studied in 30 dogs over the 8 week study period. Interestingly, the fine print at the bottom of the BrightEyes website reads: "Ethos Bright Eyes Products makes no claim that the drops cure or prevent any eye problems".
A board-certified veterinary ophthalmologist from New York has commented that these drops do not reverse cataracts. It is conceivable that the active ingredient can help to prevent the free radical damage that in some cases is responsible for causing cataracts, however, it must be given long before a cataract develops in order to have a chance of minimizing the risk of cataract development. This does not make it an appropriate choice of treatment for existing cataracts.
The good news is that dogs who have developed cataracts are often able to adapt to their new world, and can still have a fantastic quality of life, even if surgical correction is not an option. As long as inflammation associated with the cataracts is diagnosed and controlled, "curing" the cataracts is not usually necessary.